.220 Swift (5.56×56mmSR) is a semi-rimmed rifle cartridge developed by Winchester and introduced in 1935 for small game and varmint hunting. It was the first factory loaded rifle cartridge with a muzzle velocity of over 4,000 ft/s (1,200 m/s)

The prototype for the .220 Swift was developed in 1934–35 by Grosvenor Wotkyns who necked down the .250-3000 Savage as a means of achieving very high velocities. However the final commercial version developed by Winchester is based on the 6mm Lee Navy cartridge necked down. The .220 Swift was developed by Winchester and introduced in 1935 as a new caliber for their Model 54 bolt-action rifle. When the Winchester Model 70 bolt action was first issued in 1936, the .220 Swift was one of the standard calibers offered and continued to be until 1964 when it was discontinued